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1

Anti-addiction drug ibogaine inhibits hERG channels: a cardiac arrhythmia risk

Xaver Koenig, Michael Kovar, Stefan Boehm, Walter Sandtner, Karlheinz Hilber

Journal:

Addiction Biology

Year:

2012

Language:

english

File:

PDF, 180 KB

english, 2012

2

The anti-addictive drug ibogaine modulates voltage-gated ion channels and may trigger cardiac arrhythmias

Michael Kovar, Xaver Koenig, Ágnes Mike, René Cervenka, Péter Lukács, Hannes Todt, Walter Sandtner, Karlheinz Hilber

Journal:

BMC Pharmacology

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

3

Speeding the Recovery from Ultraslow Inactivation of Voltage-Gated Na+ Channels by Metal Ion Binding to the Selectivity Filter: A Foot-on-the-Door?

Szendroedi, Julia, Sandtner, Walter, Zarrabi, Touran, Zebedin, Eva, Hilber, Karlheinz, Dudley, Samuel C., Fozzard, Harry A., Todt, Hannes

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 321 KB

english, 2007

4

Occupancy of the Zinc-binding Site by Transition Metals Decreases the Substrate Affinity of the Human Dopamine Transporter by an Allosteric Mechanism

Li, Yang, Mayer, Felix P., Hasenhuetl, Peter S., Burtscher, Verena, Schicker, Klaus, Sitte, Harald H., Freissmuth, Michael, Sandtner, Walter

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 896 KB

english, 2017

5

Optical force measurements utilizing Lanthanide Binding Tags

Sandtner, Walter, Egwolf, Bernhard, Roux, Benoit, Correa, Ana M., Bezanilla, Francisco

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 100 KB

english, 2009

6

Bridging the Gap between Functional and Structural Data

Burtscher, Verena, Hotka, Matej, Stockner, Thomas, Machtens, Jan-Philipp, Sandtner, Walter

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 45 KB

english, 2019

7

Deciphering the Nature of M1R Transient Currents

Burtscher, Verena, Hasenhuetl, Peter S., Hotka, Matej, Freissmuth, Michael, Sandtner, Walter

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 47 KB

2020

8

INTERNATIONALE STREITBEILEGUNG / INTERNATIONAL CONCILIATION || „Weltraumrecht — Law of Outer Space“by Stephan Frhr; Welck; Renate Platzöder

Review by: Walter Sandtner

Journal:

Archiv des Völkerrechts

Year:

1989

Language:

german

File:

PDF, 327 KB

german, 1989

9

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

Zhu, Rong, Sinwel, Doris, Hasenhuetl, Peter S., Saha, Kusumika, Kumar, Vivek, Zhang, Peng, Rankl, Christian, Holy, Marion, Sucic, Sonja, Kudlacek, Oliver, Karner, Andreas, Sandtner, Walter, Stockner,

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 3.26 MB

english, 2016

10

Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile

Koenig, Xaver, Kovar, Michael, Rubi, Lena, Mike, Agnes K., Lukacs, Peter, Gawali, Vaibhavkumar S., Todt, Hannes, Hilber, Karlheinz, Sandtner, Walter

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.36 MB

english, 2013

11

Substrate Binding to Serotonin Transporters Reduces Membrane Capacitance

Burtscher, Verena, Hotka, Matej, Sandtner, Walter

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 42 KB

english, 2017

12

Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site

Venkatesan, SanthoshKannan, Saha, Kusumika, Sohail, Azmat, Sandtner, Walter, Freissmuth, Michael, Ecker, Gerhard F., Sitte, Harald H., Stockner, Thomas, Punta, Marco

Journal:

PLoS Computational Biology

Year:

2015

Language:

english

File:

PDF, 2.33 MB

english, 2015

13

In Vivo Measurements Of a Ca2+- And Voltage-Activated K+ Channel Intramolecular Distances Using Genetically Encoded Reporters

Zaelzer, Cristian A., Sandtner, Walter, Hyde, Clark, Latorre, Ramon, Bezanilla, Francisco

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

14

Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates

Baumann, Michael H, Bulling, Simon, Benaderet, Tova S, Saha, Kusumika, Ayestas, Mario A, Partilla, John S, Ali, Syed F, Stockner, Thomas, Rothman, Richard B, Sandtner, Walter, Sitte, Harald H

Journal:

Neuropsychopharmacology

Year:

2014

Language:

english

File:

PDF, 2.75 MB

english, 2014

15

para-Trifluoromethyl-methcathinone is an allosteric modulator of the serotonin transporter

Niello, Marco, Cintulova, Daniela, Hellsberg, Eva, Jäntsch, Kathrin, Holy, Marion, Ayatollahi, Leila H., Cozzi, Nicholas V., Freissmuth, Michael, Sandtner, Walter, Ecker, Gerhard F., Mihovilovic, Mark

Journal:

Neuropharmacology

Year:

2019

File:

PDF, 8.31 MB

2019

16

Gating currents from neuronal Kv7 channels

Miceli, Francesco, Campos, Fabiana V., Walter, Sandtner, Soldovieri, Maria Virginia, Annunziato, Lucio, Taglialatela, Maurizio, Bezanilla, Francisco

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 44 KB

english, 2009

17

A kinetic account for amphetamine-induced monoamine release

Hasenhuetl, Peter S., Bhat, Shreyas, Mayer, Felix P., Sitte, Harald H., Freissmuth, Michael, Sandtner, Walter

Journal:

The Journal of General Physiology

Year:

2018

Language:

english

File:

PDF, 2.57 MB

english, 2018

18

The synthetic cathinones, butylone and pentylone, are stimulants that act as dopamine transporter blockers but 5-HT transporter substrates

Saha, Kusumika, Li, Yang, Holy, Marion, Lehner, Kurt R., Bukhari, Mohammad O., Partilla, John S., Sandtner, Walter, Sitte, Harald H., Baumann, Michael H.

Journal:

Psychopharmacology

Year:

2018

Language:

english

File:

PDF, 665 KB

english, 2018

19

Ouabain Binding Site in a Functioning Na+/K+-ATPase

Sandtner, Walter, Egwolf, Bernhard, Khalili-Araghi, Fatemeh, Sanchez-Rodríguez, Jorge E., Roux, Benoit, Bezanilla, Francisco, Holmgren, Miguel

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 39 KB

english, 2012

20

A comparison of the transport kinetics of glycine transporter 1 and glycine transporter 2

Erdem, Fatma Asli, Ilic, Marija, Koppensteiner, Peter, Gołacki, Jakub, Lubec, Gert, Freissmuth, Michael, Sandtner, Walter

Journal:

The Journal of General Physiology

Year:

2019

Language:

english

File:

PDF, 2.48 MB

english, 2019

21

A Kinetic Assessment of Ligand Binding to Monoamine-Transporters

Hasenhuetl, Peter S., Freissmuth, Michael, Sitte, Harald H., Sandtner, Walter

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 39 KB

english, 2015

22

LRET Measurements In The Three Major Conformations Of The Shaker K Channel

Sandtner, Walter, Lacroix, Jerome, Robertson, Janice, Frezza, Ludivine, Hyde, Clark, Bezanilla, Francisco, Correa, Ana M.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 58 KB

english, 2009

23

Occupancy of the zinc-binding site by transition metals decreases the substrate affinity of the human dopamine transporter by an allosteric mechanism.

Li, Yang, Mayer, Felix P., Hasenhuetl, Peter S., Burtscher, Verena, Schicker, Klaus, Sitte, Harald H., Freissmuth, Michael, Sandtner, Walter

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 49 KB

english, 2017

24

Effects by Ibogaine on the Dopamine Transporter

Sandtner, Walter, Bulling, Simon, Schicker, Klaus, Gruber, Chrisitan, Sitte, Harald

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 33 KB

english, 2011

25

Nano-Positioning System for Structural Analysis of Functional Homomeric Proteins in Multiple Conformations

H. Clark Hyde, Walter Sandtner, Ernesto Vargas, Alper T. Dagcan, Janice L. Robertson, Benoit Roux, Ana M. Correa, Francisco Bezanilla

Journal:

Year:

2012

Language:

english

File:

PDF, 4.32 MB

english, 2012

26

A quantitative model of amphetamine action on the 5-HT transporter

Sandtner, Walter, Schmid, Diethart, Schicker, Klaus, Gerstbrein, Klaus, Koenig, Xaver, Mayer, Felix P, Boehm, Stefan, Freissmuth, Michael, Sitte, Harald H

Journal:

British Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

27

Stromal Fibroblasts in Colorectal Liver Metastases Originate From Resident Fibroblasts and Generate an Inflammatory Microenvironment

Lars Mueller, Freya A. Goumas, Marianne Affeldt, Susanne Sandtner, Ursula M. Gehling, Silke Brilloff, Jessica Walter, Nadia Karnatz, Katrin Lamszus, Xavier Rogiers, Dieter C. Broering

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 1.29 MB

english, 2007

28

Lithium Stabilizes the Inward Facing Conformation of Human Serotonin Transporter (hSERT)

Bulling, Simon J., Sandtner, Walter, Uzelac, Zeljko, Sitte, Harald

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 33 KB

english, 2011

29

Charge Movement of a Voltage-Sensitive Fluorescent Protein

Villalba-Galea, Carlos A., Sandtner, Walter, Dimitrov, Dimitar, Mutoh, Hiroki, Knöpfel, Thomas, Bezanilla, Francisco

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 2.90 MB

english, 2009

30

In Vivo Measurement of Intramolecular Distances Using Genetically Encoded Reporters

Sandtner, Walter, Bezanilla, Francisco, Correa, Ana M.

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 206 KB

english, 2007

31

A Unifying Concept of Serotonin Transporter Associated Currents

Sandtner, Walter, Schicker, Klaus, Freissmuth, Michael, Rudnick, Gary, Sitte, Harald H.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

32

Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates

Bhat, Shreyas, Hasenhuetl, Peter S, Kasture, Ameya, El-Kasaby, Ali, Baumann, Michael H, Blough, Bruce E, Sucic, Sonja, Sandtner, Walter, Freissmuth, Michael

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

33

Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures

Cervenka, Rene, Lukacs, Peter, Gawali, Vaibhavkumar S., Ke, Song, Koenig, Xaver, Rubi, Lena, Zarrabi, Touran, Hilber, Karlheinz, Sandtner, Walter, Stary-Weinzinger, Anna, Todt, Hannes

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.11 MB

english, 2018

34

LRET-based intramolecular distance measurements in LeuTAa

Azmat Sohail, Peggy Stolt-Bergner, Gerhard F Ecker, Michael Freissmuth, Thomas Stockner, Harald H Sitte, Walter Sandtner

Journal:

BMC Pharmacology

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

35

Luminescence resonance energy transfer-based intramolecular distance measurements in leucine transporter fromAquifex aeolicus

Azmat Sohail, Peggy Stolt-Bergner, Gerhard F Ecker, Michael Freissmuth, Harald Sitte, Walter Sandtner

Journal:

BMC Pharmacology

Year:

2010

Language:

english

File:

PDF, 133 KB

english, 2010

36

Deciphering structural rearrangements during transport process in the bacterial transporter GltPh, homolog to mammalian glutamate transporter

SanthoshKannan Venkatesan, Azmat Sohail, Walter Sandtner…

Journal:

BMC Pharmacology and Toxicology

Year:

2012

Language:

english

File:

PDF, 65 KB

english, 2012

37

Selectivity Filter Residues Contribute Unequally to Pore Stabilization in Voltage-Gated Sodium Channels †

Hilber, Karlheinz, Sandtner, Walter, Zarrabi, Touran, Zebedin, Eva, Kudlacek, Oliver, Fozzard, Harry A., Todt, Hannes

Journal:

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

38

An Electrophysiological Approach to Measure Changes in the Membrane Surface Potential in Real Time

Burtscher, Verena, Hotka, Matej, Freissmuth, Michael, Sandtner, Walter

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 1.76 MB

english, 2019

39

Serotonin-transporter mediated efflux: A pharmacological analysis of amphetamines and non-amphetamines

Birgit Hilber, Petra Scholze, Mario M. Dorostkar, Walter Sandtner, Marion Holy, Stefan Boehm, Ernst A. Singer, Harald H. Sitte

Journal:

Neuropharmacology

Year:

2005

Language:

english

File:

PDF, 501 KB

english, 2005

40

Fluorinated phenmetrazine “legal highs” act as substrates for high-affinity monoamine transporters of the SLC6 family

Mayer, Felix P., Burchardt, Nadine V., Decker, Ann M., Partilla, John S., Li, Yang, McLaughlin, Gavin, Kavanagh, Pierce V., Sandtner, Walter, Blough, Bruce E., Brandt, Simon D., Baumann, Michael H., S

Journal:

Neuropharmacology

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

41

Bridging the Gap between Functional and Structural Data

Burtscher, Verena, Hotka, Matej, Stockner, Thomas, Machtens, Jan-Philipp, Sandtner, Walter

Journal:

Biophysical Journal

Year:

2019

File:

PDF, 45 KB

2019

42

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter

Sonja Sucic, Stephan Dallinger, Barbara Zdrazil, Oliver Kudlacek, Walter Sandtner, Gerhard F Ecker, Michael Freissmuth, Harald H Sitte

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 65 KB

english, 2009

43

Transporters in Motion: Combining Computational Approaches and LRET-Measurements

Sitte, Harald H., Venkatesan, SanthoshKannan, Sohail, Azmat, Saha, Kusumika, Jayaraman, Kumaresan, Ecker, Gerhard F., Freissmuth, Michael, Sandtner, Walter, Stockner, Thomas

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 38 KB

english, 2015

44

Dissecting the Catalytic Cycle of the Serotonin Transporter

Hasenhuetl, Peter S., Freissmuth, Michael, Sitte, Harald H., Schicker, Klaus, Li, Yang, Sandtner, Walter

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 45 KB

english, 2016

45

para-Trifluoromethyl-methcathinone is an allosteric modulator of the serotonin transporter

Niello, Marco, Cintulova, Daniela, Hellsberg, Eva, Jäntsch, Kathrin, Holy, Marion, Ayatollahi, Leila H., Cozzi, Nicholas V., Freissmuth, Michael, Sandtner, Walter, Ecker, Gerhard F., Mihovilovic, Mark

Journal:

Neuropharmacology

Year:

2019

Language:

english

File:

PDF, 8.31 MB

english, 2019

46

A relationship between membrane permeability of amphetamines and serotonin efflux via serotonin transporters

Walter Sandtner, Klaus Gerstbrein, Harald H Sitte

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

47

The Aspartate Transporter in Motion - Combining Steered Molecular Dynamics with Lanthanide Resonance Energy Transfer based Distance Measurements

Venkatesan, SanthoshKannan, Sohail, Azmat, Saha, Kusumika, Ecker, Gerhard, Stockner, Thomas, Sandtner, Walter, Sitte, Harald

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 113 KB

english, 2014

48

Analysis of CorA-Catalyzed Mg2+ Selective Currents in Xenopus Oocytes

Dalmas, Olivier, Sandtner, Walter, Santos, Jose S., Frezza, Ludivine, Cuello, Luis G., Bezanilla, Francisco, Perozo, Eduardo

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

49

Unfolding the Structure of LeuT Employing Luminescence Resonance Energy Transfer

Sohail, Azmat, Kudlacek, Oliver, Daerr, Markus, Stolt-Bergner, Peggy, Ecker, Gerhard, Freissmuth, Michael, Wanner, Klaus, Stockner, Thomas, Sandtner, Walter, Sitte, Harald

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 86 KB

english, 2014

50

Voltage-Dependent Conformational Changes of the Voltage Sensor of KVAP Measured with LRET

Lacroix, Jerome J., Sandtner, Walter, Hyde, Clark, Bezanilla, Francisco, Correa, Ana M.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

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